Testosterone replacement therapy (TRT) is a form of medical treatment that helps restore testosterone levels to a healthy level by providing prescription testosterone. In most cases, injectable testosterone is administered either weekly or bi-weekly. This results in a steady supply of testosterone in the blood and, eventually, the reversal of low T symptoms. Hence, the goal of TRT is to re-establish and maintain proper testosterone levels. After being on TRT for a few weeks, many men notice they are able to sleep better, their sex drive is higher, they have more confidence and motivation, they have an easier time building muscle and losing fat, and their energy levels are greater. Adult males with low T are the ideal candidates for TRT since testosterone levels tend to fade as we age past our 20s. However, some younger males may be candidates for TRT if they have primary or secondary hypogonadism since these signify a dysfunction either in the testes or the brain, respectively. Regardless of what age you are, low T is not something to be taken lightly and TRT is the most effective way to treat this condition.
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Sexual dysfunction may be classified into four main groups: loss of libido, erectile dysfunction (ED), ejaculatory insufficiency, and anorgasmic states. A sexually competent male must have desire for his sex partner (libido), divert blood from the iliac artery into the corpora cavernosa to achieve penile tumescence and rigidity (erection) adequate for penetration, then discharge sperm and prostatic and seminal vesicle fluid through the urethra (ejaculation), and experience a sense of pleasure (orgasm) (5, 6).
Androgenic hormones include dihydroepiandrostenedione (DHEA), DHEA sulfate, androstenedione, testosterone and dihydrotestosterone. The most important female sex hormones which also affect male sexuality are estrogen, LH, FSH and prolactin. Cardiopulmonary bypass (CPB) for on-pump CABG can affect serum levels of androgenic hormones, especially testosterone (8).
Andropause During andropause, the male's serum testosterone levels fall, leading in many cases to erectile dysfunction.3 Males cannot achieve an erection or cannot sustain one for a sufficient time to complete sexual intercourse. The penis may gradually disengorge during intercourse. Legitimate medical interventions include testosterone, Viagra, Caverject, and devices inserted into the penis. Patients undergoing andropause oftendo not choose these therapies, opting instead to try dietary supplements. As millions of baby boomers are currently experiencing andropause, marketers offer hundreds of products allegedly beneficial in reversing impotence and enhancing male sexual performance.4
Quality of Research on Dietary Supplements When research on dietary supplements intended for sexual enhancement appears, it must be scrutinized closely to assess the soundness of the methodology employed. Two such studies explored the abilities of KyoGreen powder (barley, wheat grass, seaweed) for sexual dysfunction in men and women and ArginMax (herbs, vitamins, minerals) to enhance sexual function in males.28,29 While both studies seemed to show positive results, they are rendered virtually useless because neither study used a control group that was administered a placebo for a valid comparison. Unfortunately, much of the research on dietary supplements is hampered by profound flaws such as this that would cause the research to be rejected by the FDA if it were to be submitted through the legitimate new drug application process used for new medications.
References 1. Health quackery: Spotting health scams. National Institute on Aging. Available at: www.niapublications.org/agepages/healthqy.asp. Accessed June 29, 2007. 2. Pray WS. A History of Nonprescription Product Regulation. New York, NY: The Haworth Press, Inc.; 2003. 3. Hafez B, Hafez ES. Andropause: endocrinology, erectile dysfunction, and prostate pathophysiology. Arch Androl. 2004;50:45-68. 4. Broeder CE. Oral andro-related prohormone supplementation: do the potential risks outweigh the benefits? Can J Appl Physiol. 2003;28:102-116. 5. FTC Consumer Alert. The truth about impotence treatment claims. Federal Trade Commission. Available at: www.ftc.gov/bcp/conline/pubs/alerts/impoalrt.htm. Accessed June 29, 2007. 6. FDA warns consumers about dangerous ingredients in "dietary supplements" promoted for sexual enhancement. Food and Drug Administration. Available at: www.fda.gov/bbs/topics/NEWS/2006/NEW01409.html. Accessed June 29, 2007. 7. FDA issues dietary supplements final rule. Food and Drug Administration. Available at: www.fda.gov/bbs/topics/NEWS/2007/NEW01657.html. Accessed June 29, 2007. 8. Final rule promotes safe use of dietary supplements. Food and Drug Administration. Available at: www.fda.gov/consumer/updates/dietarysupps062207.html. Accessed June 29, 2007. 9. Final rule for current good manufacturing practices (CGMPs) for dietary supplements. Food and Drug Administration. Available at: www.cfsan.fda.gov/dms/dscgmps7.html. Accessed June 29, 2007. 10. Dietary supplement current good manufacturing practices (CGMPs) and interim final rule (IFR) facts. Food and Drug Administration. Available at: www.cfsan.fda.gov/dms/dscgmps6.html. Accessed June 29, 2007. 11. Freking K. FDA issues new safety rules for vitamins. ABC News. Available at: www.abcnews.go.com/Health/wirestory?id=3306953. Accessed June 29, 2007. 12. Zwillich T. FDA OKs dietary supplement regulations. WebMD. Available at: www.webmd.com/news/20070622/fda-oks-dietary-supplement-regulations. Accessed June 29, 2007. 13. Gammon KS. FDA issues dietary supplement rules. Available at: www.abcnews.go.com/Health/story?id=3307441&page=3. Accessed June 29, 2007. 14. Schardt D. Sex in a bottle. Center for Science in the Public Interest. Available at: www.cspinet.org/nah/10_04/sexinabottle.pdf. Accessed June 29, 2007. 15. Enzyte male enhancement testimonials. Merazon Health Products, Inc. Available at: www.enzyte-male-enhancement.com/google/testimonials.html. Accessed June 29, 2007. 16. Cohen B, Schardt D. Letter to The Honorable Deborah P. Majoras. Center for Science in the Public Interest. Available at: www.cspinet.org/new/pdf/ftcenzyteletter.pdf. Accessed June 29, 2007. 17. Enjoy natural male enhancement! Berkeley Premium Nutraceuticals, Inc. Available at: www.enzyte.com/nme.html. Accessed June 29, 2007. 18. Enzyte is trusted by over 3 million users and is the #1 selling supplement in the world for natural male enhancement. Berkeley Premium Nutraceuticals, Inc. Available at: www.enzyte.com. Accessed June 29, 2007. 19. Enzyte marketers sued. Quackwatch.com. Available at: www.quackwatch.org/02ConsumerProtection/enzyte.html. Accessed June 29, 2007. 20. Blended for real results. Berkeley Premium Nutraceuticals, Inc. Available at: www.enzyte.com/blend.html. Accessed June 29, 2007. 21. Frequently asked questions. Berkeley Premium Nutraceuticals, Inc. Available at: www.enzyte.com/faq.html. Accessed June 29, 2007. 22. Paeth G. Enzyte maker under fire. The Cincinnati Post. Available at: www.cincypost.com/2004/08/14/complaint081404.html. Accessed June 29, 2007. 23. "Smiling Bob" not smiling anymore. ConsumerAffairs.Com Inc. Available at: www.consumeraffairs.com/news04/2006/03/smiling_bob.html. Accessed June 29, 2007. 24. Marketer of "enhancement" pill Enzyte to pay restitution, change practices in settlement over negative option plan. Missouri Attorney General Jay Nixon. Available at: www.ago.mo.gov/newsreleases/2006/030206b.htm. Accessed June 29, 2007. 25. Attorney General Lockyer announces settlement requiring maker of "Smiling Bob" erectile dysfunction product to provide consumers restitution. California Department of Justice. Available at: www.ag.ca.gov/newsalerts/release.php?id=1266&year=2006&month=3&PHPSESSID=5d5320608e1af33b6ab42dca5...&PHPSESSID=5d5320608e1af33b6ab42dca5. Accessed June 29, 2007. 26. AG sues herbal supplement company for misleading Oregonians about the pills' effectiveness and the "free" trial offer. Oregon Department of Justice. Available at: www.doj.state.or.us/releases/2005/rel061605.shtml. Accessed June 29, 2007. 27. Berkeley Premium Nutraceuticals, six individuals indicted for fraudulent business practices in connection with sales of dietary supplements. Available at: www.usdoj.gov/usao/ohs/Press/09-21-06.pdf. Accessed June 29, 2007. 28. Lau BH, Lau EW. Kyo-Green improves sexual dysfunction in men and women. Med Sci Monit. 2003;9:PI12-18. 29. Ito T, Kawahara K, Das A, et al. The effects of ArginMax, a natural dietary supplement for enhancement of male sexual function. Hawaii Med J . 1998;57:741-744.
What if I told you pomegranate could help all of your sexual health problems, from low testosterone and diminished libido to erectile dysfunction to even prostate cancer? This superfood is filled with antioxidants that have proven results to help both men and women have better sex lives. This fruit can increase testosterone levels, improve sperm quality, and increase sex drive and mood.
This is critical to testosterone levels. Too much estrogen can interfere with libido, hurt erectile health, and damage bone strength. Plus, estrogen actually blocks testosterone production. High levels of estrogen actually further diminish T levels to create an unhealthy imbalance of hormones that are destructive to male sexual health.
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